ORBIT Bleeding Risk Score

Major Bleeding Risk in Patients on Anticoagulation for AF

Older age (≥75 years)

Reduced hemoglobin/hematocrit or history of anemia Men: Hgb <13 g/dL or Hct <40% · Women: Hgb <12 g/dL or Hct <36%

Bleeding history Any prior GI bleeding, intracranial hemorrhage, or hemorrhagic stroke

Insufficient kidney function eGFR <60 mL/min/1.73m²

Treatment with antiplatelet agents Aspirin, clopidogrel, or other antiplatelet therapy

Total Score 0

Risk Category Low

Annual Major Bleed Rate 2.4 per 100 patient-years

Low bleeding risk — standard anticoagulation with routine monitoring.