Clinical Resources

PESI & sPESI Score

Pulmonary Embolism Severity Index — 30-Day Mortality Risk

Full PESI

Age

years

Age in years is added directly to the score

Male sex

+10

Cancer Active or history within past year

+30

Heart failure

+10

Chronic lung disease

+10

Heart rate ≥ 110 bpm

+20

Systolic BP < 100 mmHg

+30

Respiratory rate ≥ 30/min

+20

Temperature < 36°C

+20

Altered mental status Disorientation, lethargy, stupor, or coma

+60

SpO₂ < 90%

+20

Full PESI Result

PESI Score —

Risk Class —

30-Day Mortality —

Enter age to calculate full PESI score.

Simplified PESI (sPESI)

Age > 80 years

+1

Cancer

+1

Heart failure or chronic lung disease

+1

Heart rate ≥ 110 bpm

+1

Systolic BP < 100 mmHg

+1

SpO₂ < 90%

+1

sPESI Result

sPESI Score 0

Risk Category Low risk

30-Day Mortality 1.0%

sPESI = 0 — Low risk. 30-day mortality ~1%. Consider outpatient treatment if clinically appropriate.

Reference

Aujesky D et al. 2005 — Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med.

Jiménez D et al. 2010 — Simplification of the Pulmonary Embolism Severity Index for prognostication in patients with acute symptomatic PE. Arch Intern Med.