Clinical Resources

AHA PREVENT Calculator

2023 AHA PREVENT Equations — 10- and 30-Year CVD Risk

The PREVENT equations replace the Pooled Cohort Equations (PCE) and incorporate kidney function, metabolic markers, and social determinants. For ages 30–79 without prior ASCVD.

Range: 30–79
Optional — enhances risk estimate in diabetic patients
Optional — urine albumin-to-creatinine ratio

Key Differences from Pooled Cohort Equations

  • Kidney function: Incorporates eGFR and optionally UACR as primary risk enhancers.
  • Metabolic health: HbA1c provides more nuanced diabetes risk assessment than binary DM status.
  • Race-free: Does not use race as a variable — addresses health equity concerns of the prior PCE model.
  • Broader outcomes: Predicts total CVD (ASCVD + HF) rather than only atherosclerotic events.
  • Age range: Validated for ages 30–79 (vs. 40–79 for PCE).

Reference

Khan SS et al. (2024) — Development and Validation of the AHA PREVENT Equations. Circulation. 149(6):e430–e449.