Clinical Resources

SCORE2 / SCORE2-OP

ESC 2021 — 10-Year Fatal and Non-Fatal CVD Risk

SCORE2 (ages 40–69) and SCORE2-OP (ages 70–89) estimate 10-year risk of fatal and non-fatal cardiovascular events. Risk thresholds are calibrated by European CVD risk region.

Range: 40–89
1 mmol/L = 38.67 mg/dL

ESC 2021 Treatment Thresholds

  • Age < 50: Low <2.5%, Moderate 2.5–7.5%, High ≥7.5%
  • Age 50–69: Low <5%, Moderate 5–10%, High ≥10%
  • Age ≥ 70: Low <7.5%, Moderate 7.5–15%, High ≥15%

Reference

SCORE2 Working Group & ESC Cardiovascular Risk Collaboration (2021). Eur Heart J. 42(25):2439–2454.