Clinical Quick Reference — Preoperative Evaluation & Management of Noncardiac Surgery
This guideline supersedes the 2014 ACC/AHA Perioperative Evaluation and Management of Patients Undergoing Noncardiac Surgery. Major updates include stepwise assessment framework, functional capacity emphasis (DASI scoring), perioperative troponin monitoring for MINS, refined statin/beta-blocker recommendations, SGLT2i withdrawal protocols, and updated guidance on valvular disease, arrhythmias, and CIED management.
| Risk Score | Key Components | Prediction |
|---|---|---|
| RCRI | Age, high-risk surgery, CAD, HF, CVA, Cr >2, DM on insulin | 30-day MI/cardiac death |
| NSQIP | Age, Cr, DM, HF, CVA, surgery type, functional status | 30-day MACE |
| AUB-HAS2 | Age ≥75, Cr >1.5, renal disease, high-risk surgery, emergency | 30-day death/MI/stroke |
| DASI | 12 activities (stairs, sexual relations, heavy work) | Functional capacity (METs) |
COR 1 Obtain in patients with known CAD, arrhythmia, structural heart disease, or elevated-risk surgery. COR 3 NOT recommended in asymptomatic low-risk patients.
COR 1 Indicated for suspected severe AS/MR or HF symptoms. NOT recommended routinely in asymptomatic stable patients.
COR 2a Selectively in elevated-risk with poor functional capacity (<4 METs). COR 3 NOT recommended in low-risk or adequate-capacity patients.
COR 2a May be considered in elevated-risk with low clinical suspicion of CAD and normal functional capacity. Not replacing stress testing.
COR 2a BNP/NT-proBNP for age ≥45 with CVD symptoms or eGFR <30. COR 1 High-sensitivity troponin baseline + 24–48 h postop in elevated-risk for MINS surveillance.
COR 1 Continue chronic statin therapy perioperatively. Do NOT discontinue.
Hold morning of surgery; restart postoperatively once stable. Caution: rebound hypertension upon withdrawal.
| Stent Type | Minimum Delay | DAPT Duration |
|---|---|---|
| BMS | ≥30 days COR 1 | Aspirin + clopidogrel ≥1 month |
| DES | ≥3–6 months COR 1 | Aspirin + P2Y12i ≥6 months |
COR 2a Withdraw 3–4 days preoperatively (euglycemic DKA risk). Restart postoperatively when orally tolerant.
COR 1 Reasonable for ACS (STEMI/high-risk NSTEMI). COR 2a Consider for non-left main CAD ≥50% in selected elevated-risk. COR 1 CABG preferred for left main >50%.
BMS: Proceed ≥30 days with aspirin + clopidogrel. DES: Defer ≥3–6 months; individualize based on ACS risk and procedure urgency.
Hypertension control paramount. Continue antihypertensives. Volume optimization critical. No specific perioperative intensification beyond routine management.
COR 2a Group 1 PH undergoing elevated-risk NCS: specialty consultation recommended. Continue targeted therapies. Consider invasive hemodynamic monitoring and ICU care.
COR 1 Symptomatic severe AS: delay elective NCS or pursue TAVR/SAVR first. COR 2a Asymptomatic with LVEF ≥50%: reasonable to proceed cautiously with elective low-risk NCS after multidisciplinary discussion.
COR 1 Severe MS undergoing elevated-risk NCS: perioperative invasive hemodynamic monitoring to guide intraoperative management.
Mild-to-moderate without LV dysfunction: minimal risk. Severe AR: maintain preload, avoid tachycardia. Severe MR: optimize afterload reduction.
COR 1 Preoperative AF: optimize rate control; assess anticoagulation per CHA₂DS₂-VASc. COR 2a New-onset perioperative AF: aggressive rate control; consider anticoagulation (high stroke risk).
| Device Type | Perioperative Strategy | COR |
|---|---|---|
| Transvenous PM/ICD | Reprogram to asynchronous (VVI/DOO) if pacemaker-dependent; magnet placement 5 cm from generator; postop interrogation mandatory | COR 1 |
| Leadless PM | No magnet effect; no reprogramming needed; confirm postop functionality | COR 1 |
| Subcutaneous ICD | EMI above groin: program therapies off; confirm battery postop | COR 1 |
COR 1 Elevated-risk patients: baseline high-sensitivity troponin preop + 24–48 h postop. MINS (troponin elevation without overt ischemia) occurs in 7–25%; associated with increased 30-day mortality.
Estimate glomerular filtration rate for kidney function staging
Cockcroft-Gault equation for renal function
European perioperative mortality risk model
10-year cardiovascular disease risk
Acute coronary syndrome risk stratification
Atrial fibrillation stroke risk
Bleeding risk in anticoagulation
QT interval correction for heart rate
Pulmonary embolism risk stratification
Alternative CVD risk model
Acute coronary syndrome mortality risk